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产品中心 诊断抗原 IVD抗原

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Human RBP4 , His tag

Plasma retinol-binding protein (PRBP,RBP)

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A9007
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Plasma retinol-binding protein (PRBP; RBP)

  • Accession

    P02753

  • 表达序列

    Protein sequence(P02753, Glu19-Leu201, with C-10*His) ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLLGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    Theoretical:22.7kDa Actual:24kDa

  • 纯度

    ＞90% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

背景介绍

  • Retinol binding protein 4, also known as RBP4, is a transporter protein[5] for retinol (vitamin A alcohol). It is mainly, though not exclusively, synthesized in the liver and circulates in the bloodstream as a hepatokine bound to retinol in a complex with transthyretin. RBP4 has been a drug target for ophthalmology research due to its role in vision. RBP4 may also be involved in metabolic diseases as suggested by recent studies. Retinol-binding protein 4 in urine (uRBP4) is a functional biomarker of disease of the proximal renal tubule1. When proximal tubular dysfunction interferes with reabsorption of proteins filtered by the renal glomerulus, striking increases of uRBP4 are found.

  • 生物活性

    • Immobilized Human RBP4, His tag at 1 μg/mL (50 μL/well) can bind RBP4 Recombinant Rabbit mAb (S-693-111) (Cat. No. S0B0605) with EC50 of 3.388-3.785 ng/ ml.

  • 电泳

    • 2μg（R: reducing conditions）

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