热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 诊断抗原 骨代谢抗原

所有图片（1/1）

Human PINP, His tag

Procollagen I N-Terminal Propeptide

价格 ￥3,280.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A7001
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Procollagen I N-Terminal Propeptide

  • Accession

    P02452

  • 表达序列

    Protein sequence(P02452, Gln23-Pro161, with C-10*His)
    QEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    Theoretical: 15.9kDa Actual:23kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 ℃ to -70 °C as supplied.

    1 month, 2 to 8 °C under sterile conditions after reconstitution.

    Please avoid repeated freeze-thaw cycles.

背景介绍

  • Type 1 collagen is the major collagen in the body and is mainly found in mineralised bone. It has a triple helical structure consisting of one α1 and two α2 chains which are linked by disulphide bonds. The molecule is synthesised as procollagen which is proteolytically cleaved to remove both the N‐ and C- terminal parts of the molecule prior to the assembly of the remainder into the collagen matrix. The N‐ and C‐terminals are released into the circulation stoichiometrically and thus reflect the synthesis of new type 1 collagen.The amino-terminal propeptide of type I procollagen (PINP) is probably the most specific and sensitive marker of bone formation. PINP is a useful marker for monitoring the efficacy of osteoporosis therapy with anabolic agents, but it is also one of the best bone turnover markers for monitoring the efficacy of anti-resorptive therapy.

  • 电泳

    • 2μg (R: reducing conditions)

评论(0)