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Human REG1A Protein, His Tag

Lithostathine-1-alpha,Islet cells regeneration factor (ICRF),Islet of Langerhans regenerating protein (REG),Pancreatic stone protein (PSP),Pancreatic thread protein (PTP),Regenerating islet-derived protein 1-alpha (REG-1-alpha),Regenerating protein I alpha,PSPS,PSPS1,REG

价格 500.00 1-2周
货号 S0A6070
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产品介绍 评论(0)

产品规格
  • 物种

    Human
  • 分子别名

    Lithostathine-1-alpha, Islet cells regeneration factor (ICRF), Islet of Langerhans regenerating protein (REG), Pancreatic stone protein (PSP), Pancreatic thread protein (PTP), Regenerating islet-derived protein 1-alpha (REG-1-alpha), Regenerating protein I alpha, PSPS, PSPS1, REG
  • Accession

    P05451
  • 表达序列

    Protein sequence (P05451, Gln23-Asn166, with C-His Tag) QEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN

  • 表达宿主

    HEK293
  • 分子量

    Predicted MW: 18 kDa Observed MW: 18 kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <1EU/μg
  • 标记

    Unconjugated
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍
  • Lithostathine-1-alpha, also known as Regenerating islet-derived protein 1 alpha (REG1A), is a secreted protein encoded by the REG1A gene. It is primarily produced by the pancreas and plays a role in promoting cell proliferation and regeneration. Its name originates from its initial identification as a protein that inhibits calcium carbonate crystal formation, potentially preventing pancreatic stone formation. However, its primary significance lies in its function as a acute-phase reactant and its strong association with inflammatory and malignant conditions. REG1A is markedly overexpressed in diseases such as chronic pancreatitis and pancreatic ductal adenocarcinoma, making it a promising biomarker for early detection and monitoring of these conditions.

  • 电泳

    • 2μg(R: reducing conditions)

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