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Nipah Virus Glycoprotein G Protein, His Tag

Glycoprotein G

价格 ￥1,000.00 （ 1-2周）
货号 S0A6061
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 分子别名

    Glycoprotein G

  • Accession

    Q9IH62

  • 表达序列

    Protein sequence (Q9IH62, Gln71-Thr602, with N-His Tag) QNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINENVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVVGQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 61 kDa Observed MW: 70-90 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • The Nipah virus Glycoprotein G (NiV-G) is a surface attachment protein essential for viral entry. It forms tetramers that recognize and bind to cellular receptors ephrin-B2 and ephrin-B3, which are highly conserved in mammals. Following receptor binding, the fusion protein (F) is triggered to mediate membrane fusion. NiV-G is a primary target for neutralizing antibodies, making it a key component of vaccine and antiviral research. Due to Nipah virus's high pathogenicity and biosafety level 4 classification, studies of G protein structure and function are critical for developing countermeasures against this deadly paramyxovirus.

  • 生物活性

    • Immobilized Nipah Virus Glycoprotein G Protein, His Tag at 5 μg/mL (100 μL/well) can bind Human Ephrin-B2 / EFNB2 Protein, Fc tag (MALS verified) with EC50 of 7.4-9.6 ng/ml.

  • 电泳

    • 2μg（R: reducing conditions）

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