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Human Kallikrein 6 Protein, His Tag

Kallikrein-6,Neurosin,Protease M,SP59,Serine protease 18,Serine protease 9,Zyme,KLK6,PRSS18,PRSS9

价格 ￥1,400.00 （ 1-2周）
货号 S0A6059
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产品介绍

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产品规格

  • 物种

    Human

  • 分子别名

    Kallikrein-6, Neurosin, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme, KLK6, PRSS18, PRSS9

  • Accession

    Q92876

  • 表达序列

    Protein sequence (Q92876, Glu17-Lys244, with C-His Tag) EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 26.8 kDa Observed MW: 10, 20 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • Kallikrein-6 (KLK6), also known as neurosin or zyme, is a serine protease belonging to the kallikrein family of proteins. It is predominantly expressed in the central nervous system and has been implicated in various physiological and pathological processes, including demyelination, inflammation, and neurodegeneration. Elevated KLK6 levels are associated with multiple sclerosis, Alzheimer's disease, and certain cancers. The protein functions by cleaving extracellular matrix components and myelin basic protein, contributing to tissue remodeling and disease progression. KLK6 is also being explored as a potential biomarker and therapeutic target.

  • 电泳

    • 2μg（R: reducing conditions）

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