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Human Galectin-3, His tag

35 kDa lectin,Carbohydrate-binding protein 35 (CBP 35),Galactose-specific lectin 3,Galactoside-binding protein (GALBP),IgE-binding prtein,LGALS3,MAC2

价格 ￥1,000.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A6015
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    35 kDa lectin, Carbohydrate-binding protein 35 (CBP 35), Galactose-specific lectin 3, Galactoside-binding protein (GALBP), IgE-binding prtein, LGALS3, MAC2

  • Accession

    P17931

  • 表达序列

    Protein sequence(P17931, Ala2-Ile250, with C-10*His)
    ADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMIGGGGSHHHHHHHHHH

  • 表达宿主

    E.coli

  • 分子量

    Theoretical: 27.8kDa Actual: 28kDa

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

  • 溶解方法

    Reconstitute no more than 1mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, -20 to -70 °C as supplied.
    · 6 months, -20 to -70 °C under sterile conditions after reconstitution.
    · 1 week, 2 to 8 °C under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

背景介绍

  • Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is approximately 30 kDa and, like all galectins, contains a carbohydrate-recognition-binding domain (CRD) of about 130 amino acids that enable the specific binding of β-galactosides. Galectin-3 (Gal-3) is also a member of the beta-galactoside-binding protein family that plays an important role in cell-cell adhesion, cell-matrix interactions, macrophage activation, angiogenesis, metastasis, apoptosis. Galectin-3 is increasingly being used as a diagnostic marker for different cancers. It can be screened for and used as a prognostic factor to predict the progression of the cancer. Galectin-3 has varying effects in different types of cancer. One approach to cancers with high galectin-3 expression is to inhibit galectin-3 to enhance treatment response.

  • 生物活性

    • Immobilized Human Galectin-3, His tag at 1 μg/mL (50 μL/well) can bind Galectin-3 Recombinant Rabbit mAb (SDT-370-111) (S0B2197) with EC50 of 9.036-11.94 ng/ml.

  • 电泳

    • 2μg (R: reducing conditions)

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