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Human TIMP-1, His tag

Erythroid-potentiating activity (EPA),Fibroblast collagenase inhibitor (Collagenase inhibitor),metalloproteinases inhibitor 1

价格 ￥2,970.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A6009
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Erythroid-potentiating activity (EPA), Fibroblast collagenase inhibitor (Collagenase inhibitor), metalloproteinases inhibitor 1

  • Accession

    P01033

  • 表达序列

    Protein sequence (P01033, Cys24-Ala207, with C-10*His) CTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRSQIAGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    Theoretical: 22.3kDa Actual: 33kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 ℃ to -70 °C as supplied.

    1 month, 2 to 8 °C under sterile conditions after reconstitution.

    Please avoid repeated freeze-thaw cycles.

背景介绍

  • TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein with a molecular weight of 28 kDa.TIMP1 is expressed from several tissues of organisms. TIMP1 is an inhibitory molecule that regulates matrix metalloproteinases (MMPs), and disintegrin-metalloproteinases (ADAMs and ADAMTSs). In regulating MMPs, TIMP1 plays a crucial role in extracellular matrix (ECM) composition, wound healing, and pregnancy.

  • 生物活性

    • Immobilized Human TIMP-1, His tag at 2 μg/mL (50 μL/well) can bind TIMP1 Recombinant Rabbit mAb (S-213-124) (Cat. No. S0B0793) with EC50 of 7.3-8.9 ng/mL.

  • 电泳

    • 2μg（R: reducing conditions）

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