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Mouse CD96 Protein, His Tag

T-cell surface protein tactile,Cell surface antigen CD96,T cell-activated increased late expression protein

价格 ￥760.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A5010
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    T-cell surface protein tactile, Cell surface antigen CD96, T cell-activated increased late expression protein

  • Accession

    Q3U0X8

  • 表达序列

    Protein sequence (Q3U0X8, Val22-Met536, with C-His tag) VWEELFNVGDDVYALPGSDINLTCQTKEKNFLVQMQWSKVTDKNDMIALYHPQYGLYCGQEHACESQVAATETEKGVTNWTLYLRNISSALGGKYECIFTLYPEGIKTTVYNLIVEPYTQDEHNYTIEIETNRTLEIPCFQNTSSEIPPRFTFSWLVEKDGVEEVLFTHHHHVNNSTSFKGRIRLGGDYRLHLSPVQIQDDGRTFSCHLTVNPLKAWKMSTTVKVFAKPEILMTVENSTMDVLGERVFTCLLKNVFPKANITWFIDGRFLQGNEEGIYITNEEKNCSSGFWELKSVLTRMHSGPSQSNNMTAWCMALSPGPRNKMWNTSSQPITVSFDSVIAPTKHLPTVTGSTLGTQPFSDAGVSPTGYLATPSVTIVDENGLTPDATPQTSNSSMTTKDGNYLEASSGTDAKNSSRAAASSKSGSWPFPFTSPPEWHSLPGTSTGPQEPDSPVSWIPSEVHTSAPLDASLAPHDTIISTTTEFPNVLTTANGTTKIDHGPITSIIVNQPSDGM

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 58.5 kDa Observed MW: 100-130 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    with C-His tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • CD96 (also known as TACTILE) is an immune checkpoint protein belonging to the immunoglobulin superfamily, closely related to TIGIT and CD226 (DNAM-1). It is primarily expressed on natural killer (NK) cells and T cells, where it interacts with its ligand, CD155 (PVR), and to a lesser extent, CD112 (PVRL2). CD96 functions as a co-inhibitory receptor, dampening immune responses by competing with the activating receptor CD226 for the same ligands.

  • 生物活性

    • Immobilized Mouse CD96 Protein, His Tag at 2 μg/mL (100 μL/well) can bind Recombinant Mouse PVR/CD155 Protein, C-hFc&Avi with EC50 of 99-126 ng/ml.

  • 电泳

    • 2μg（R: reducing conditions）

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