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物种
Human分子别名
Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1), T-cell immunoglobulin mucin receptor 1 (TIM; TIM-1), T-cell membrane protein 1, CD365, HAVCR1Accession
Q96D42表达序列
Protein sequence(Q96D42, Ser21-Gly295, with C-10*His) SVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTTDGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGGGGGSHHHHHHHHHH
表达宿主
HEK293分子量
Theoretical:31.1kDa Actual: 39, 75-110kDa纯度
＞95% by SDS-PAGE
内毒素含量
<1EU/μg标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.
KIM-1 (Kidney Injury Molecule -1) is a protein the most highly upregulated in injured kidneys by various types of insults. Its upregulation during renal injury has been found in the kidneys of the vertebrates such as Zebrafish and humans. A soluble form of human KIM-1 can be detected in the urine of patients with ATN and may serve as a useful biomarker for renal proximal tubule injury facilitating the early diagnosis of the disease and serving as a diagnostic discriminator.
生物活性
Immobilized Human Kim-1, His tag at 2 μg/mL (50 μL/well) can bind KIM-1 Recombinant Rabbit mAb (S-932-2) (Cat. No. S0B0604) with EC50 of 3.341-4.967 ng/ ml.
电泳
2μg(R: reducing conditions)
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