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产品中心 细胞因子 白细胞介素

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Human IL-7 Protein, His Tag

Interleukin-7,IL7

价格 ￥1,100.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A4049
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Interleukin-7, IL7

  • Accession

    P13232

  • 表达序列

    Protein sequence (P13232, Asp26-His177, with C-His Tag) DCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH

  • 分子量

    Predicted MW: 19.1 kDa Observed MW: 19, 24, 28 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells, but is not produced by normal lymphocytes. IL-7 stimulates the differentiation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells. It also stimulates proliferation of all cells in the lymphoid lineage (B cells, T cells and NK cells). It is important for proliferation during certain stages of B-cell maturation, T and NK cell survival, development and homeostasis. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. IL-7 could also be beneficial in improving immune recovery after allogenic stem cell transplant.

  • 生物活性

    • Immobilized Human IL-7 Protein, His tag at 2 μg/mL (100 μL/well) can bind IL-7R alpha/CD127 Fc Chimera Protein, Human (Cat. No. UA010892) with EC50 of 9.73-15.58 ng/ml.

  • 电泳

    • 2μg（R: reducing conditions）

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