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Human IFN-α2, His Tag

Interferon alpha-2,Interferon alpha-A,IFNA2

价格 ￥1,500.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A4005
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Interferon alpha-2, Interferon alpha-A,IFNA2

  • Accession

    P01563

  • 表达序列

    Protein sequence(P01563, Cys24-Glu188, with C-10*His) CDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKEGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    Theoretical:20.9kDa Actual:20,24kDa

  • 纯度

    >95% by SDS-PAGE

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70℃ as supplied.

    1 month, 2 to 8℃ under sterile conditions after reconstitution.

    Please avoid repeated freeze-thaw cycles.

背景介绍

  • Human interferon alpha-2 (IFNα2) is a cytokine belonging to the family of type I IFNs. IFNα2 is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection.IFNα2 was the first subtype to be characterized in the early eighties. As a result, IFNα2 was widely used in basic research to elucidate biological activities, structure and mechanism of action of type I IFNs. IFNα2 was also the first IFN to be produced by the pharmaceutical industry for use as a drug.In addition to their antiviral activity, type I IFNs also inhibit the proliferation of cells and regulate the activation of the immune system.

  • 生物活性

    • Immobilized Human IFN-α2, His Tag at 4 μg/mL (50 μL/well) can bind Recombinant Human IFNAR2 Protein with EC50 of 0.214-0.257 μg/ ml.

  • 电泳

    • 2μg（R: reducing conditions）

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