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产品中心 诊断抗原 CD分子抗原

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Mouse SLAMF8 Protein, His Tag

SLAM family member 8,B-lymphocyte activator macrophage expressed,CD353,Blame

价格 ￥400.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A1157
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    SLAM family member 8, B-lymphocyte activator macrophage expressed, CD353, Blame

  • Accession

    Q9D3G2

  • 表达序列

    Protein sequence (Q9D3G2, Val21-Asp231, with C-His Tag) VQVLSKVGDSELLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLKPGDSGNFSVLMVDTGGQTWTQTLYLKVYDAVPKPEVQVFTAAAEETQPLNTCQVFLSCWAPNISDITYSWRWEGTVDFNGEVRSHFSNGQVLSVSLGLGDKDVAFTCIASNPVSWDMTTVTPWESCHHEAASGKASYKD

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 25.1 kDa Observed MW: 30-40 kDa

  • 纯度

    ＞90% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • SLAMF8 (SLAM Family Member 8), also known as BLAME (B-lymphocyte activator macrophage expressed), is a cell surface receptor belonging to the signaling lymphocyte activation molecule (SLAM) family. Primarily expressed on myeloid cells such as macrophages and dendritic cells, it plays a crucial role in immune regulation. Unlike other SLAM family members, SLAMF8 acts as a negative regulator of inflammatory responses. Research indicates its involvement in macrophage polarization, phagocytosis, and the maintenance of immune homeostasis. It is also implicated in the pathogenesis of inflammatory bowel disease and the tumor microenvironment, making it a potential biomarker for immune-related disorders.

  • 电泳

    • 2μg（R: reducing conditions）

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