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物种
Human分子别名
Intercellular adhesion molecule 2, ICAM-2Accession
P13598表达序列
Protein sequence (P13598, Lys25-Gln223, with C-His Tag) KVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSDSQ
表达宿主
HEK293分子量
Predicted MW: 23.8 kDa Observed MW: 43-60 kDa纯度
＞95% by SDS-PAGE内毒素含量
<1EU/μg标记
Unconjugated性状
Lyophilized Powder缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
CD102, also known as Intercellular Adhesion Molecule-2 (ICAM-2), is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is constitutively expressed on endothelial cells, leukocytes, and platelets. As a ligand for the leukocyte integrin LFA-1 (αLβ2), CD102 plays a crucial role in mediating leukocyte adhesion, transmigration across the endothelium, and immune synapse formation during inflammation and immune responses. Its expression is less inducible by inflammatory cytokines compared to ICAM-1. CD102 is essential for lymphocyte homing and the recruitment of immune cells to sites of infection or injury, contributing to both innate and adaptive immunity.
电泳
2μg（R: reducing conditions）
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