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产品中心 诊断抗原 CD分子抗原

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Human LAIR1/CD305 Protein, His tag

Leukocyte-associated immunoglobulin-like receptor 1,LAIR-1,hLAIR1,CD305,LAIR1

价格 ￥500.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A1151
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305, LAIR1

  • Accession

    Q6GTX8

  • 表达序列

    Protein sequence (Q6GTX8, Gln22-His163, with C-His tag) QEEDLPRPSISAEPGTVIPLGSHVTFVCRGPVGVQTFRLERDSRSTYNDTEDVSQASPSESEARFRIDSVREGNAGLYRCIYYKPPKWSEQSDYLELLVKESSGGPDSPDTEPGSSAGPTQRPSDNSHNEHAPASQGLKAEH

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 17.2 kDa Observed MW: 30 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    with C-His tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • LAIR1 (Leukocyte-Associated Immunoglobulin-like Receptor 1) is an inhibitory immune receptor primarily expressed on myeloid cells and lymphocytes. It regulates immune responses by transmitting inhibitory signals through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) upon binding to ligands like collagen or other extracellular matrix components. LAIR1 modulates inflammation, autoimmunity, and antitumor immunity, acting as a checkpoint to prevent excessive immune activation.

  • 电泳

    • 2μg（R: reducing conditions）

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