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分子别名
Complement C3d receptor 2, CR2Accession
M3WDJ8表达序列
Protein sequence (M3WDJ8, Ile21-Pro1038, with C-His tag) ISCDPPPPIKNGWSSYSSGPIPLNTVIRYTCSGNFRLIGERVIFCISKDQVKAIWDKGAPVCEYYNKNSFCSEPIVPGGYRDKTSRPPYRHGDSVTFTCNTNFTMKGNKSVWCRANRTWGPTPLPICESDFPQECTSLPKIPNGHHTGESVGSFAPGLSVTYSCEPGYLLVGEKTIRCLSSGKWSAAFPGCKEAQCEPPGPFLNGEIEGPPSLRVGVTVNFYCNEGYWLQGQPSSRCVIAGQRASWTRMPVCKEILCGPPPSILNGRHTGNPSGNIPYGSMVTYACDPDPEKGVSFILTGKKTIHCTANSQKTGGVWSGPAPRCELSSSAIQCPPPQIPRGHISSGWKEQYSYNDTVVFACTFGFTMKGSKVTRCNGQGAWEPSVPVCEKECQAPPKILNGQKEDGHMVRFDPGTSIKYRCDPGYVLVGEKSIRCTSEGVWTPTAPECKVAECEPIEKQVFKRPRDQFIRPDVNSSCDEGYRLGGSVYQLCQGAIPWFMEHRLCEEITCPPPPVIYNGKHTRSSSENVPYGTTVTYTCNPGPESGVEFILVGESTIRCISNDQERGIWSGPAPVCKLSLPAVQCPPAHVANGYKISGKEAPYFYNDSVTFKCNKGFTLKGSSQIRCKANNTWDPEIPVCEKGCPPPFGLQHGRHTGGNRVLFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEEAPCQPVREDLREPPVHSHVVLVNTSCQEGYQLTGHAYQKCQDAENRVWFQKIPLCKAVHCPPPPVIDHGRPRGVMAEHFLYGNEVSYECDQGFSLLGEKNIRCISDSKGHGSWSGPTPQCFKSPPVTHCPNPEVKHGYKLNKTRSSYAHNDTVYVACNPGFIMNGSNLIRCHTSNQWVPGVPTCIKMAFSGCQPPLDIPNGNHTGGDMARFSPGMSILYSCDQGYLLVGEAFLLCTHEGTWSQPAPYCKEVNCSSPEYINGIQKGLEPGKMYQYGAIVTLECEEGYTLEGSPQSQCQDDHRWNPPLAVCKSPASLAP
表达宿主
HEK293分子量
Predicted MW: 113.1 kDa Observed MW: 160 kDa纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
Unconjugated标签
with C-His tag性状
Lyophilized Powder缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells express CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation. Complement receptor 2 interacts with CD19, and, on mature B cells, forms a complex with CD81 (TAPA-1). The CR2-CD19-CD81 complex is often called the B cell co-receptor complex, because CR2 binds to opsonized antigens through attached C3d (or iC3b or C3dg) when the B-cell receptor binds antigen. This results in the B cell having greatly enhanced response to the antigen.
电泳
2μg（R: reducing conditions）
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