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Human SIGLEC7 Protein, His tag

Sialic acid-binding Ig-like lectin 7,Siglec-7,Adhesion inhibitory receptor molecule 1 (AIRM-1),CDw328,D-siglec,QA79 membrane protein,p75,CD328,AIRM1

价格￥1,650.00 （供应商现货： 3-5个工作日）

货号 S0A1137

数量

产品介绍

产品介绍评论(0)

产品规格

物种

Human
分子别名

Sialic acid-binding Ig-like lectin 7, Siglec-7, Adhesion inhibitory receptor molecule 1 (AIRM-1), CDw328, D-siglec, QA79 membrane protein, p75, CD328, AIRM1
Accession

Q9Y286
表达序列

Protein sequence (Q9Y286, Gln19-Leu353, with C-His tag) QKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLL
表达宿主

HEK293
分子量

Predicted MW: 38.6 kDa Observed MW: 55-70 kDa
纯度

＞95% by SDS-PAGE
内毒素含量

<0.1EU/μg
标记

Unconjugated
标签

with C-His tag
性状

Lyophilized Powder
缓冲体系

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
溶解方法

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
储存条件

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

背景介绍

Siglecs (Sialic acid-binding immunoglobulin-type lectins) are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. There are 14 different mammalian Siglecs, providing an array of different functions based on cell surface receptor-ligand interactions. Sialic acid-binding Ig-like lectin 7 is a protein that in humans is encoded by the SIGLEC7 gene. SIGLEC7 has also been designated as CD328. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity.