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物种
Human分子别名
C-type lectin domain family 9 member A, CD370Accession
Q6UXN8表达序列
Protein sequence (Q6UXN8, Lys57-Val241, with C-hFc tag) KLLQVSTIAMQQQEKLIQQERALLNFTEWKRSCALQMKYCQAFMQNSLSSAHNSSPCPNNWIQNRESCYYVSEIWSIWHTSQENCLKEGSTLLQIESKEEMDFITGSLRKIKGSYDYWVGLSQDGHSGRWLWQDGSSPSPGLLPAERSQSANQVCGYVKSNSLLSSNCSTWKYFICEKYALRSSV
表达宿主
HEK293分子量
Predicted MW: 47.3 kDa Observed MW: 60 kDa
纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
Unconjugated标签
with C-hFc tag性状
Lyophilized Powder缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
C-type lectin domain family 9 member A is a protein that in humans is encoded by the CLEC9A gene. CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells. CLEC9A ligation enhances antigen uptake and processing, leading to presentation on MHC class I and cytotoxic T cell (CTL) priming. Its recognition of filamentous actin in dead cells is important for triggering an immune response to necrotic cell debris. CLEC9A is also required for the presentation of viral proteins and the subsequent CTL-mediated killing of virus-infected cells. CLEC9A signaling triggers activation of the tyrosine kinase Syk.
电泳
2μg（R: reducing conditions）
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