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Mouse BST2 Protein, His tag

Bone marrow stromal antigen 2,BST-2,HM1.24 antigen,CD317

价格 1,350.00 1-2周
货号 S0A1133
规格
数量
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产品介绍 评论(0)

产品规格
  • 物种

    Mouse
  • 分子别名

    Bone marrow stromal antigen 2, BST-2, HM1.24 antigen, CD317
  • Accession

    Q8R2Q8
  • 表达序列

    Protein sequence (Q8R2Q8, Ala53-Asn151, with C-His tag) ANSVACRDGLRAQAECRNTTHLLQRQLTRTQDSLLQAETQANSCNLTVVTLQESLEKKVSQALEQQARIKELENEVTKLNQELENLRIQKETSSTVQVN

  • 表达宿主

    HEK293
  • 分子量

    Predicted MW: 12.9 kDa Observed MW: 18-25 kDa
  • 纯度

    >90% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    with C-His tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍
  • Bone marrow stromal antigen 2, also known as CD317, is a lipid raft associated protein that is encoded by the BST2 gene. This protein is constitutively expressed in mature B cells, plasma cells and plasmacytoid dendritic cells, and in many other cells, it is only expressed as a response to stimuli from IFN pathway. BST2 is a cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 has been shown as a Type-I-IFN biomarker using flow cytometry, B cell BST2 was used as a Cell-Specific Assay for Response to Type I Interferon Predicts Clinical Features and Flares in Systemic Lupus Erythematosus. BST2 has also been predicted to be involved in cell adhesion and cell migration. It has also been identified as the protein that help stabilize lipid rafts by joining nearby lipid rafts to form a cluster.

  • 电泳

    • 2μg(R: reducing conditions)

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