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物种
Felis catus分子别名
T-cell surface antigen T4/Leu-3Accession
P79355表达序列
Protein sequence (P79355, Met1-Thr413 (Lys20Glu, Ser84Cys, Val103Ile, Asn115Asp, Ser142Thr, Ser169Gly & insertions of SerThr between Thr148 and Ser149), with C-10*His) MNQGAVFRHLLLVLQLVMLEAAVPQGKEVVLGKAGGTAELPCQASQKKYMTFTWRLSSQVKILESQHSSLCLTGSSKLKTRFECKKILWDQGSFPLVIKSLQIADSGIYTCEVEDKKREVELLVFGLTAKVDPSGSGGSSSTSTSTSTSTSIYLLQGQSLTLTLESPSGSNPSVQWKGPGNKSKSGVHSLSLSQLELQESGTCTCTVSQSQKTLVFNTNILVLAFRKVSNTVYAKEGEQVEFSFPLNFEDENLMGNLRWKAEGAPSSLLWISFTLKNKQLSVKEVDPYSKLQMMDSLPLRFTLPNVLSRYAGSGNLTLVLDKGQLQQEVKLVVMRVTQSGNNLTCEVLGPTSPELTLSLKLKGQAAKVSKQQKMVRVEDAEAGTWQCLLSHKDKVLLASKAEVLPPVLTRTWTGGGGSHHHHHHHHHH
表达宿主
HEK293分子量
Predicted MW: 46.8 kDa Observed MW: 50 kDa纯度
＞95% by SDS-PAGE内毒素含量
<1EU/μg标签
with C-10*His性状
Lyophilized Powder缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.
CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4+ T helper cells are white blood cells that are an essential part of the immune system. They are called helper cells because one of their main roles is to send signals to other types of immune cells, including CD8 killer cells, which then destroy the infectious particle. If CD4 cells become depleted, the body is left vulnerable to a wide range of infections that it would otherwise have been able to fight. CD4 continues to be expressed in most neoplasms derived from T helper cells. The antigen has also been associated with a number of autoimmune diseases such as type I diabetes mellitus.
电泳
2 μg（R: reducing conditions）
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