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产品中心 诊断抗原 CD分子抗原

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Human CD44, His tag

CDw44 Epican Extracellular matrix receptor III (ECMR-III) GP90 lymphocyte homing/adhesion receptor HUTCH-I Heparan sulfate proteoglycan Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 (PGP-1) Phagocytic glycoprotein I (PGP-I)

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A1028
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    CDw44 Epican Extracellular matrix receptor III (ECMR-III) GP90 lymphocyte homing/adhesion receptor HUTCH-I Heparan sulfate proteoglycan Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 (PGP-1) Phagocytic glycoprotein I (PGP-I)

  • Accession

    P16070

  • 表达序列

    Protein sequence(P16070, Gln21-Pro220, with C-10*His) QIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    Theoretical:23.7kDa Actual:35-50kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

背景介绍

  • The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is a multistructural and multifunctional cell surface molecule involved in cell proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines, chemokines, and growth factors to the corresponding receptors, and docking of proteases at the cell membrane, as well as in signaling for cell survival. All these biological properties are essential to the physiological activities of normal cells, but they are also associated with the pathologic activities of cancer cells. Experiments in animals have shown that targeting of CD44 by antibodies, antisense oligonucleotides, and CD44-soluble proteins markedly reduces the malignant activities of various neoplasms, stressing the therapeutic potential of anti-CD44 agents.

  • 电泳

    • 2μg（R: reducing conditions）

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