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Mycobacterium tuberculosis fbpA/Ag85A Protein, His Tag

Diacylglycerol acyltransferase/mycolyltransferase Ag85A,DGAT,Acyl-CoA:diacylglycerol acyltransferase,Antigen 85 complex A (85A,Ag85A),Fibronectin-binding protein A (Fbps A),mpt44,MT3911

Datasheet COA

价格￥600.00 （供应商现货： 3-5个工作日）

货号 S0A0200

数量

产品介绍

产品介绍评论(0)

产品规格

分子别名

Diacylglycerol acyltransferase/mycolyltransferase Ag85A, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex A (85A; Ag85A), Fibronectin-binding protein A (Fbps A), mpt44, MT3911
Accession

P9WQP2
表达序列

Protein sequence (P9WQP2, Phe44-Ala338, with N-His Tag) FSRPGLPVEYLQVPSPSMGRDIKVQFQSGGANSPALYLLDGLRAQDDFSGWDINTPAFEWYDQSGLSVVMPVGGQSSFYSDWYQPACGKAGCQTYKWETFLTSELPGWLQANRHVKPTGSAVVGLSMAASSALTLAIYHPQQFVYAGAMSGLLDPSQAMGPTLIGLAMGDAGGYKASDMWGPKEDPAWQRNDPLLNVGKLIANNTRVWVYCGNGKPSDLGGNNLPAKFLEGFVRTSNIKFQDAYNAGGGHNGVFDFPDSGTHSWEYWGAQLNAMKPDLQRALGATPNTGPAPQGA
表达宿主

HEK293
分子量

Predicted MW: 33.3 kDa Observed MW: 33 kDa
纯度

＞95% by SDS-PAGE
内毒素含量

<1EU/μg
标记

Unconjugated
性状

Lyophilized Powder
缓冲体系

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
溶解方法

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
储存条件

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

背景介绍

Ag85A, a member of the Antigen 85 complex, is a pivotal mycolyltransferase secreted by Mycobacterium tuberculosis and other mycobacteria. This enzyme is essential for constructing the unique, impermeable mycobacterial cell wall. It catalyzes the transfer of mycolic acids—long-chain fatty acids critical for pathogenicity—onto the arabinogalactan layer of the cell envelope, forming a protective lipid barrier. Ag85A also exhibits diacylglycerol acyltransferase activity, contributing to trehalose dimycolate (cord factor) synthesis. As one of the most abundant and immunodominant proteins secreted by the bacillus, Ag85A is a major target of the host immune response and a leading candidate for subunit vaccines against tuberculosis.