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Human SLP-76 Protein, His Tag

Lymphocyte cytosolic protein 2,SH2 domain-containing leukocyte protein of 76 kDa,SLP-76 tyrosine phosphoprotein (SLP76),LCP2

价格 ￥1,200.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A0198
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产品介绍

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产品规格

  • 物种

    Human

  • 分子别名

    Lymphocyte cytosolic protein 2, SH2 domain-containing leukocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein (SLP76), LCP2

  • Accession

    Q13094

  • 表达序列

    Protein sequence (Q13094, Met1-Pro533, with C-His Tag) MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 61.9 kDa Observed MW: 75-100 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • Lymphocyte cytosolic protein 2 (LCP2), also commonly known as SLP-76, is a crucial adaptor protein expressed in hematopoietic cells, including T cells, B cells, macrophages, and platelets. It plays a central role in coupling activated immunoreceptors, such as the T-cell receptor (TCR), to multiple downstream signaling pathways. Upon phosphorylation, LCP2 nucleates a large signaling complex that regulates critical cellular processes including proliferation, differentiation, adhesion, and cytokine production. It is essential for proper immune cell development and function. Deficiencies in LCP2 signaling are linked to immunodeficiencies and platelet abnormalities, highlighting its fundamental importance in immunity and hemostasis.

  • 电泳

    • 2μg（R: reducing conditions）

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