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Human TMED4 Protein, His Tag

Transmembrane emp24 domain-containing protein 4,Endoplasmic reticulum stress-response protein 25 (ERS25),GMP25iso,Putative NF-kappa-B-activating protein 156,p24 family protein alpha-3 (p24alpha3),ERS25

Datasheet COA

价格￥500.00 （供应商现货： 3-5个工作日）

货号 S0A0196

数量

产品介绍

产品介绍评论(0)

产品规格

物种

Human
分子别名

Transmembrane emp24 domain-containing protein 4, Endoplasmic reticulum stress-response protein 25 (ERS25), GMP25iso, Putative NF-kappa-B-activating protein 156, p24 family protein alpha-3 (p24alpha3), ERS25
Accession

Q7Z7H5
表达序列

Protein sequence (Q7Z7H5, Leu30-Arg194, with C-His Tag) LYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQR
表达宿主

HEK293
分子量

Predicted MW: 20.9 kDa Observed MW: 20 kDa
纯度

＞95% by SDS-PAGE
内毒素含量

<1EU/μg
标记

Unconjugated
性状

Lyophilized Powder
缓冲体系

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
溶解方法

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
储存条件

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

背景介绍

Transmembrane emp24 domain-containing protein 4 (TMED4) is a member of the p24 family of type I transmembrane proteins, which are involved in endoplasmic reticulum (ER)-to-Golgi vesicular transport. It functions as a cargo receptor, facilitating the selective packaging of glycosylphosphatidylinositol (GPI)-anchored proteins and other specific clients into COPII-coated transport vesicles. TMED4 forms hetero-oligomeric complexes with other family members to ensure efficient cargo sorting and maintenance of cellular homeostasis. Its role is crucial for proper protein secretion and cellular trafficking pathways. Dysregulation of TMED4 has been implicated in certain diseases, including cancer.