Mouse Tim-4 Protein, His Tag
T-cell immunoglobulin and mucin domain-containing protein 4,TIMD-4,Spleen,mucin-containing,knockout of lymphotoxin protein (SMUCKLER),T-cell immunoglobulin mucin receptor 4 (TIM-4),T-cell membrane protein 4
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物种
Mouse分子别名
T-cell immunoglobulin and mucin domain-containing protein 4, TIMD-4, Spleen, mucin-containing, knockout of lymphotoxin protein (SMUCKLER), T-cell immunoglobulin mucin receptor 4 (TIM-4), T-cell membrane protein 4Accession
Q6U7R4表达序列
Protein sequence (Q6U7R4, Ala23-Thr279, with C-His Tag) ASEDTIIGFLGQPVTLPCHYLSWSQSRNSMCWGKGSCPNSKCNAELLRTDGTRIISRKSTKYTLLGKVQFGEVSLTISNTNRGDSGVYCCRIEVPGWFNDVKKNVRLELRRATTTKKPTTTTRPTTTPYVTTTTPELLPTTVMTTSVLPTTTPPQTLATTAFSTAVTTCPSTTPGSFSQETTKGSAFTTESETLPASNHSQRSMMTISTDIAVLRPTGSNPGILPSTSQLTTQKTTLTTSESLQKTTKSHQINSRQT
表达宿主
HEK293分子量
Predicted MW: 29.5 kDa Observed MW: 75-100 kDa纯度
＞95% by SDS-PAGE内毒素含量
<1EU/μg标记
Unconjugated性状
Lyophilized Powder缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
TIMD-4, also known as TIM-4, is a member of the T-cell immunoglobulin and mucin domain (TIM) family, which plays a crucial role in immune regulation. Expressed primarily on antigen-presenting cells (APCs), such as macrophages and dendritic cells, TIMD-4 binds to phosphatidylserine (PS) on apoptotic cells, mediating their phagocytic clearance and maintaining immune tolerance. It also interacts with TIM-1 on T cells, influencing T-cell activation and cytokine production. TIMD-4 is implicated in autoimmune diseases, allergies, and infections due to its role in modulating immune responses.
电泳
2μg（R: reducing conditions）
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