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产品中心 药物靶点和Fc受体 药物靶点

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Mouse alpha-Synuclein Protein, His Tag

Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor (NACP),Snca,Syn

价格 ￥400.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A0183
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor (NACP), Snca, Syn

  • Accession

    O55042

  • 表达序列

    Protein sequence (O55042, Met1-Ala140, with N-His tag) MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYPQEGILEDMPVDPGSEAYEMPSEEGYQDYEPEA

  • 表达宿主

    E.coli

  • 分子量

    Predicted MW: 16.8 kDa Observed MW: 18 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    with N-His tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • Alpha-synuclein is a neuronal protein that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. It is abundant in the brain, while smaller amounts are found in the heart, muscle and other tissues. In the brain, alpha-synuclein is found mainly in the axon terminals of presynaptic neurons. Within these terminals, alpha-synuclein interacts with phospholipids and proteins. It plays a role in restricting the mobility of synaptic vesicles, consequently attenuating synaptic vesicle recycling and neurotransmitter release.

  • 生物活性

    • Immobilized Mouse alpha-Synuclein Protein, His Tag at 1 μg/mL (100 μL/well) can bind α-Synuclein Recombinant Rabbit mAb (S-441-86) (Cat. No. S0B0344) with EC50 of 3.5-4.4 ng/ml.

  • 电泳

    • 2μg（R: reducing conditions）

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