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Human CHODL Protein, His tag

Chondrolectin,Transmembrane protein MT75,C21orf68,PRED12

价格 ￥1,400.00 （ 1-2周）
货号 S0A0155
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Chondrolectin, Transmembrane protein MT75, C21orf68, PRED12

  • Accession

    Q9H9P2

  • 表达序列

    Protein sequence (Q9H9P2, Arg22-Ala211, with C-His tag) RRVVSGQKVCFADFKHPCYKMAYFHELSSRVSFQEARLACESEGGVLLSLENEAEQKLIESMLQNLTKPGTGISDGDFWIGLWRNGDGQTSGACPDLYQWSDGSNSQYRNWYTDEPSCGSEKCVVMYHQPTANPGLGGPYLYQWNDDRCNMKHNYICKYEPEINPTAPVEKPYLTNQPGDTHQNVVVTEA

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 23.2 kDa Observed MW: 34 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    with C-His tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • Chondrolectin is a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. This protein has been shown to localise to the perinucleus. The exact function of chondrolectin is unknown but it has been shown to be a marker of fast motor neurons in mice, and is involved in motor neuron development and growth in zebrafish (Danio rerio). Furthermore, human chondrolectin has been shown to localise to motor neurons within the spinal cord. Chondrolectin is alternatively spliced in the spinal cord of mouse models of the neuromuscular disease, spinal muscular atrophy (SMA), which predominantly affects lower motor neurons. Increased levels of chondrolectin in a zebrafish model of SMA results in significant improvements in disease-related motor neuron defects.

  • 电泳

    • 2μg（R: reducing conditions）

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