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Human RUNX1, His tag

Acute myeloid leukemia 1 protein,Core-binding factor subunit alpha-2 (CBF-alpha-2),Oncogene AML-1,PEA2-alpha B,PEBP2-alpha B,SL3-3 enhancer factor 1 alpha B subunit,SL3/AKV core-binding factor alpha B subunit,AML1,CBFA2

价格 ￥250.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A0028
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2 (CBF-alpha-2), Oncogene AML-1,PEA2-alpha B,PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit, AML1, CBFA2

  • Accession

    Q01196

  • 表达序列

    Protein sequence(Q01196 Ser50-Leu183, with C-10*His)
    SMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLGGGGSHHHHHHHHHH

  • 表达宿主

    E.coli

  • 分子量

    Theoretical:16.7kDa Actual: 17kDa

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, 1mM DTT, pH7.4. Normally trehalose is added as protectant before lyophilization.

  • 溶解方法

    Reconstitute no more than 0.1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, -20 to -70 °C as supplied.
    · 6 months, -20 to -70 °C under sterile conditions after reconstitution.
    · 1 week, 2 to 8 °C under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

背景介绍

  • Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) is a protein that in humans is encoded by the RUNX1 gene. RUNX1 is a transcription factor that regulates the differentiation of hematopoietic stem cells into mature blood cells. In addition it plays a major role in the development of the neurons that transmit pain. It belongs to the Runt-related transcription factor (RUNX) family of genes which are also called core binding factor-α (CBFα). RUNX proteins form a heterodimeric complex with CBFβ which confers increased DNA binding and stability to the complex.

  • 电泳

    • 2μg (R: reducing conditions)

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