热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 诊断抗原 激素

所有图片（1/2）

Human IGFBP-1, His Tag

IBP-1,IGF-binding protein 1,Placental protein 12 (PP12)

价格 ￥3,200.00 （ 供应商现货 ： 3-5个工作日）
货号 S0A0008
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    IBP-1, IGF-binding protein 1, Placental protein 12 (PP12)

  • Accession

    P08833

  • 表达序列

    Protein sequence (P08833, Ala26-Asn259 with C-10*His) APWQCAPCSAEKLALCPPVSASCSEVTRSAGCGCCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEAGSPESPESTEITEEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFNVQNGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    Theoretical: 26.9kDa Actual: 30kDa

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 ℃ to -70 °C as supplied.
    1 month, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Serum IGFBP-1 provided high diagnostic accuracy of early-stage ESCC, EJA, stomach and cancer.

  • 生物活性

    • Immobilized Human IGFBP-1, His Tag at 2 μg/mL (100 μL/well) can bind IGFBP1 Recombinant Rabbit mAb (SDT-196-47) (Cat. No. S0B0225) with EC50 of 1.5-2.5 ng/ml.

  • 电泳

    • 2μg (R: reducing conditions)

评论(0)