FGF-1/FGF-Acidic Protein, Bovine
Fibroblast growth factor 1,FGF-1,Acidic eye-derived growth factor II (EDGF II),Acidic fibroblast growth factor (aFGF),Endothelial cell growth factor (ECGF),Heparin-binding growth factor 1 (HBGF-1),Prostatropin
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物种
Bovine分子别名
Fibroblast growth factor 1,FGF-1,Acidic eye-derived growth factor II (EDGF II),Acidic fibroblast growth factor (aFGF),Endothelial cell growth factor (ECGF),Heparin-binding growth factor 1 (HBGF-1),Prostatropin,Accession
P03968表达序列
Ala2-Asp155表达宿主
E.coli分子量
18 kDa (Reducing)
纯度
>95% by SDS-PAGE and HPLC.内毒素含量
<0.1EU/μg活性
EC50 < 1ng/ml标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20mM Tris, 200mM NaCl, pH8.0溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
Nat Rev Drug Discov. 2009 Mar;8(3):235-53.
Fibroblast Growth Factor-Acidic (FGF-Acidic), also known as FGF-1, is a member of the fibroblast growth factor family that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and angiogenesis. FGF-Acidic is a potent mitogen that stimulates the growth and survival of a wide range of cell types, including fibroblasts, endothelial cells, and smooth muscle cells. It is involved in tissue repair, wound healing, and embryonic development.
Bovine FGF-Acidic refers to the version of this growth factor derived from bovine (cow) sources. Bovine FGF-Acidic shares high sequence homology (92%) with human FGF-Acidic and exhibits similar biological activities.
生物活性
Measured in a cell proliferation assay using Balb/c 3T3 mouse fibroblast cells. The EC50 for this effect is less than 1ng/ml.
电泳
2μg (R: reducing condition, N: non-reducing condition).
体积排阻色谱(SEC-HPLC)
>95% as determined by SEC-HPLC.
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