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产品中心 ELISA试剂盒 OneStep ELISA 试剂盒

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Human ST2 OneStep ELISA kit

价格 ￥3,000.00 （ 供应商现货 ： 3-5个工作日）
货号 S0C3010
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产品介绍

产品介绍 评论(0)

产品规格

  • 抗原名称

    ST2

  • 免疫原

    Recombinant Protein

  • 抗体类型

    Recombinant mAb

  • 反应种属 ?

    Hu

  • 纯化方式

    Protein A

  • 储存条件

    2 to 8 °C as supplied.

试剂盒参数

    • Precision

      Intra-assay: 4%；

      Inter-assay: 4.8%

    • Sample type

      Cell culture supernatant, Serum, Plasma

    • Assay type

      Sandwich (quantitative)

    • Sensitivity

      6.8 pg/ml

    • Range

      31.25 pg/ml - 2000 pg/ml

    • Recovery

      Cell culture supernatant 105%

      Serum 107%

      Plasma 93%

    • Assay time

      60 minutes

    • Species reactivity

      Human
背景介绍

  • The ST2 cardiac biomarker (also known as soluble interleukin 1 receptor-like 1) is a protein biomarker of cardiac stress encoded by the IL1RL1 gene. ST2 signals the presence and severity of adverse cardiac remodeling and tissue fibrosis, which occurs in response to myocardial infarction, acute coronary syndrome, or worsening heart failure. ST2 provides prognostic information that is independent of other cardiac biomarkers such as BNP, NT-proBNP, highly sensitive troponin, GDF-15, and galectin-3. One study indicated that discrimination is independent of age, body mass index, history of heart failure, anemia and impaired kidney function or sex.sST2(Soluble ST2) is a biomarker for risk stratification in patients with heart failure (HF) and prognostic assessment. Compared with BNP and NT-proBNP, ST2 is not affected by age, factors such as BMI and renal insufficiency.Different with so many other heart markers, the level of ST2 varies rapidly with the patient's condition. This means that ST2 can help clinicians respond faster. The increase of sST2 level (> 35ng/ml) was highly correlated with the severity of heart failure which can be used to predict readmission and mortality.

  • ELISA

    • Standard curve

      Example of human ST2 standard curve in Assay Diluent #1.

    • Linearity

      The concentrations of ST2 were measured and interpolated from the target standard curves and corrected for sample dilution.

      Sample is undiluted samples are as follows: HUVEC cells were seeded in EGM-2 media until confluent. An aliquot of the cell culture supernate (20%) was removed, assayed for human ST2, and measured 13,106 pg/mL.

    • Linearity

      The concentrations of ST2 were measured and interpolated from the target standard curves and corrected for sample dilution.

      Sample is undiluted samples are as follows: 6 individual healthy human donors serum (S) and plasma (P) were measured (10%).

    • Leading Competitor comparison

    • Protocol Diagram

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