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宿主来源
Rabbit抗原名称
CD94分子别名
Natural killer cells antigen CD94; KP43; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor; KLRD1免疫原
Recombinant Protein细胞定位
Cell membraneAccession
Q13241克隆号
S-2616-17抗体类型
Recombinant mAb抗体同种型
IgG同型对照
S0B8556反应种属 ?
Hu阳性样本
Human Peripheral Blood cells纯化方式
Protein A浓度
0.2 mg/ml标记
FITC性状
Liquid缓冲体系
PBS, 1% BSA, 0.09% sodium azide
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Hu
CD94, encoded by KLRD1, is a type II transmembrane C-type lectin glycoprotein expressed predominantly on natural killer (NK) cells and subsets of CD8⁺ T cells, where it covalently assembles with NKG2A, C, E or F subunits to form disulfide-linked heterodimers that recognize the non-classical MHC-I molecule HLA-E (or Qa-1 in mice) and deliver either inhibitory or activating signals that finely tune cytotoxicity, cytokine secretion and survival of effector lymphocytes, thereby playing a central role in innate and adaptive immunity, tumor immune evasion, viral defense and pregnancy tolerance.
流式分析
Flow cytometric analysis of CD94 expression on human peripheral blood cells. Human peripheral blood cells were stained with APC Mouse Anti-Human CD56 Antibody and either FITC Rabbit IgG Isotype Control (left panel) or SDT FITC Rabbit Anti-Human CD94 Antibody (right panel) at 5 μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
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