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Rabbit抗原名称
Amyloid beta 1-40分子别名
Aβ1-40免疫原
Synthetic PeptideAccession
P05067克隆号
SDT-1548-52抗体类型
Recombinant mAb抗体同种型
IgG应用
Sandwich ELISA反应种属 ?
Hu, Ms交叉反应
No cross-reactivity against with Amyloid beta 1-42
纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
Amyloid beta 1-40 (Aβ1-40) is a 40-residue peptide derived from the amyloid precursor protein (APP) through sequential cleavage by β-secretase and γ-secretase. It is one of the major forms of amyloid beta peptides, along with Aβ1-42, and constitutes a significant portion of the amyloid plaques found in the brains of Alzheimer's disease patients. Unlike its more pathogenic counterpart Aβ1-42, Aβ1-40 is considered less prone to aggregation and plaque formation. However, it still plays a role in the disease pathology and has been implicated in neuroinflammation and cerebrovascular dysfunction. Additionally, Aβ1-40 has been found to have non-pathological functions and is more abundant in the brain compared to Aβ1-42.
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