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宿主来源
Rabbit抗原名称
GH分子别名
Somatotropin; Growth hormone (GH; GH-N); Growth hormone 1; Pituitary growth hormone; GH1免疫原
Recombinant ProteinAccession
P01241克隆号
SDT-234-270抗体类型
Recombinant mAb抗体同种型
IgG应用
Sandwich ELISA, CLIA反应种属 ?
Hu交叉反应
No cross-reactivity against IGFBP3, IGF-1, FSH, hCG, LH, PRL, TSH
纯化方式
Protein A浓度
2 mg/ml纯度
>95% by HPLC标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt, 2 to 8 °C as supplied
Growth hormone is synthesized primarily by somatotropin in the anterior pituitary and stored in secretory granules. GH is a pleiotropic cytokine that exerts its biological effects by binding to transmembrane GH receptors present in many cell types. hGH stimulates hepatic insulin-like growth factor-1 and mobilizes fatty acids from fat deposits to the liver. GH can act directly or indirectly through IGF-1 on B cells, T cells, NK cells, macrophages, and neutrophils to exert immunomodulatory activity. Insufficient secretion of hGH results in dwarfism in children, and excessive secretion results in gigantism in children or acromegaly in adults.
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