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Rabbit分子别名
Neurofilament light, NfL免疫原
Recombinant ProteinAccession
P07196克隆号
SDT-635-214抗体类型
Recombinant mAb抗体同种型
IgG应用
Sandwich ELISA反应种属 ?
Hu, Ms交叉反应
Does not recognize GFAP纯化方式
Protein A浓度
2 mg/ml纯度
>95% by HPLC标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
Neurofilament light chain polypeptide (NFL), like NFM and NFH, is an important component of neurofilaments and maintains neuronal caliber. NFs are abundant proteins that are exclusively expressed in neurons, they may serve as a marker of neuronal degradation. Under normal conditions, NFL is released at low level from axons; however, this rate increases with age and following neuroaxonal damage. Therefore, abnormal, elevated levels of NFL can be detected in cerebrospinal fluid and blood in various acute and chronic neurological disorders. Monitoring NFL levels in CSF or blood is useful in clinical diagnostic evaluations for predicting the progression of various acute and chronic neurological diseases, as well as for assessing treatment efficacy.
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