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Rabbit抗原名称
PIIINP分子别名
Procollagen III N-terminal propeptide免疫原
Recombinant ProteinAccession
P02461克隆号
SDT-149-57抗体类型
Recombinant mAb应用
Sandwich ELISA反应种属 ?
Hu交叉反应
Does not recognize PINP, Laminin, Collagen IV纯化方式
Protein A浓度
2 mg/ml纯度
>95% by HPLC标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 |
|---|---|
| Sandwich ELISA | N/A |
Procollagen III N-terminal propeptide (PIIINP) is cleaved from procollagen III during collagen synthesis. Thus, circulating PIIINP increases during stimulation of collagen synthesis, and serum-PIIINP can be useful in the diagnosis and monitoring of a range of diseases characterised by increased collagen III deposition. PIIINP as a single marker is currently used in Denmark for monitoring disease activity in scleroderma and methotrexate-induced liver fibrosis. Besides, PIIINP forms part of the Elevated Liver Fibrosis (ELF) test, together with hyaluronic acid and tissue inhibitor of metalloproteinases (TIMP)-1, which has been demonstrated to be sensitive for alcoholic liver fibrosis.
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