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宿主来源
Rabbit抗原名称
Thrombin分子别名
N/A免疫原
Recombinant ProteinAccession
P00734克隆号
SDT-293-14抗体类型
Rabbit mAb应用
Sandwich ELISA反应种属 ?
Hu交叉反应
Does not recognize antithromnin III, PIC complex, tPA-PAI-1 complex纯化方式
Protein A浓度
2 mg/ml纯度
>95% by HPLC标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
| 应用 | 稀释度 |
|---|---|
| Sandwich ELISA | N/A |
Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot. Thrombin–antithrombin complex (TAT) is a protein complex of thrombin and antithrombin. It is a marker of net activation of coagulation. TAT is formed in response to the high thrombin level caused by coagulation following a ruptured vessel. Since thrombin is rapidly bound by antithrombin, TAT is a useful measure for thrombin level in the blood. Thrombin can pass the blood–brain barrier, destroying neurons and potentially causing cerebral edemas. The half-life of TAT is approximately 15 minutes.
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