Von Willebrand Factor Recombinant Rabbit mAb (S-663-120)

vWF,F8VWF

Datasheet COA

价格￥600.00 （供应商现货： 3-5个工作日）

货号 S0B0776

规格

25μl100μl1ml

数量

产品介绍

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产品规格

宿主来源

Rabbit
抗原名称

Von Willebrand Factor
分子别名

vWF, F8VWF
免疫原

Synthetic Peptide
细胞定位

Secreted
Accession

P04275
克隆号

S-663-120
抗体类型

Recombinant mAb
抗体同种型

IgG
反应种属 ?

Hu
纯化方式

Protein A
浓度

1 mg/ml
标记

Unconjugated
性状

Liquid
缓冲体系

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件

12 months from date of receipt / reconstitution, -20 °C as supplied
应用
稀释度

应用稀释度

IHC-P 1:200

应用	稀释度
IHC-P	1:200

背景介绍

Von Willebrand Factor (VWF) is a large multimeric plasma glycoprotein primarily produced by endothelial cells and megakaryocytes. It is found in subendothelial matrices, plasma, and platelets. VWF is synthesized in endothelial cells in the form of Weibel-Palade bodies and in platelets, it is stored in the α-granules. VWF promotes the adhesion and aggregation of platelets at sites of vascular injury, which is a crucial step in the hemostatic process. VWF also serves as a molecular chaperone for coagulation factor VIII, transporting it to sites of injury, stabilizing its heterodimeric structure, and protecting it from premature clearance from the plasma. Furthermore, VWF forms molecular bridges between subendothelial collagen matrices and platelet surface receptor complexes GPIb-IX-V, further facilitating platelet adhesion to sites of vascular injury.

免疫组化
- IHC shows positive staining in paraffin-embedded human colon. Anti- Von Willebrand Factor antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
- IHC shows positive staining in paraffin-embedded human cardiac muscle. Anti- Von Willebrand Factor antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
- IHC shows positive staining in paraffin-embedded human skeletal muscle. Anti- Von Willebrand Factor antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
- IHC shows positive staining in paraffin-embedded human hemangioma of liver. Anti- Von Willebrand Factor antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
- IHC shows positive staining in paraffin-embedded human bladder cancer. Anti- Von Willebrand Factor antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
- IHC shows positive staining in paraffin-embedded human cervical squamous cell carcinoma. Anti- Von Willebrand Factor antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
- IHC shows positive staining in paraffin-embedded human lung carcinoma. Anti- Von Willebrand Factor antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.