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Rabbit抗原名称
sFlt-1/VEGF Receptor 1分子别名
VEGFR-1, FRT免疫原
Recombinant Protein细胞定位
SecretedAccession
P17948-2克隆号
SDT-233-29抗体类型
Recombinant mAb应用
IHC-P反应种属 ?
Hu纯化方式
Protein A浓度
0.25 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 |
|---|---|
| IHC-P | 1:1000 |
Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells, increasing the vascular permeability, promoting cell migration, etc. VEGF binds to tyrosine kinase cell receptors (VEGFRs): VEGFR-1 [Fms-like tyrosine kinase 1 (Flt-1)], VEGFR-2 [kinase insert domain receptor (KDR) in human; fetal liver kinase 1 (Flk-1) in mouse] and VEGFR-3 [Fms-like tyrosine kinase 4 (Flt-4)]. While VEGFR-1 and VEGFR-2 are expressed predominantly on vascular endothelial cells, VEGFR-3 is expressed especially on lymphatic endothelial cells [PMID: 30173249].
免疫组化
![item.picture[0].fileOrgName](https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/56249d9b-97b4-4c1b-a4d0-c3951caa6086.jpg)
IHC shows positive staining in paraffin-embedded human placenta. Anti-sFlt-1/VEGF Receptor 1 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
![item.picture[0].fileOrgName](https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/12dadd54-0d08-4058-8f30-a2b4bd28a261.jpg)
IHC shows positive staining in paraffin-embedded human tonsil. Anti-sFlt-1/VEGF Receptor 1 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
![item.picture[0].fileOrgName](https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/5fb63cf3-fd11-416d-97fa-b13a02477e5d.jpg)
IHC shows positive staining in paraffin-embedded human breast cancer. Anti-sFlt-1/VEGF Receptor 1 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
![item.picture[0].fileOrgName](https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/0ba573cf-c32b-46e3-a98e-2c03399bb810.jpg)
IHC shows positive staining in paraffin-embedded human endometrial cancer. Anti-sFlt-1/VEGF Receptor 1 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
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