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产品中心 细胞因子 白细胞介素

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Human IL-28A Protein, His tag

Interferon lambda-2,IFN-lambda-2,Cytokine Zcyto20,Interleukin-28A (IL-28A),IFNL2,IL28A,ZCYTO20

价格 ￥1,200.00 （ 1-2周）
货号 S0A4047
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A (IL-28A), IFNL2, IL28A, ZCYTO20

  • Accession

    Q8IZJ0

  • 表达序列

    Protein sequence (Q8IZJ0, Val26-Val200, with C-His tag) VPVARLHGALPDARGCHIAQFKSLSPQELQAFKRAKDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALVDVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTFNLFRLLTRDLNCVASGDLCV

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 21.4 kDa Observed MW: 24 kDa

  • 纯度

    ＞90% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    with C-His tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

背景介绍

  • Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an "antiviral state" by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G (Interferon Stimulated Gene Factor 3). IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29. Their classification as Interferons is due to their ability to induce an antiviral state, while their additional classification as cytokines is due to their chromosomal location as well as the fact that they are encoded by multiple exons, as opposed to a single exon, as most type-I IFNs are. IL-28 has also been shown to play a role in the adaptive immune response.

  • 电泳

    • 2 μg（R: reducing conditions）

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